MODIFIED NON-CYTOTOXIC PROTEASES

The present invention relates to a modified polypeptide comprising a non-cytotoxic protease, a translocation domain, a destructive protease cleavage site and a Targeting Moiety that binds to a Binding Site on a nerve cell, wherein after cleavage of the destructive cleavage site the polypeptide has r...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	FOSTER, KEITH, ALAN, CHADDOCK, JOHN, ANDREW
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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