CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF

The present invention relates to novel metalloproteinase inhibitors having an aryloxybenzenesulfonamide moiety and a carbamoylphosphonic acid moiety, to pharmaceutical compositions comprising them, and to their uses in the prevention and/or treatment of disease or disorder associated with MMP.

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Hauptverfasser: BREUER, ELI, FRANT, JULIA, HOFFMAN, AMNON, AINELLY, VEERENDHAR, REICH, REUVEN
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Sprache:eng ; fre ; ger
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creator BREUER, ELI
FRANT, JULIA
HOFFMAN, AMNON
AINELLY, VEERENDHAR
REICH, REUVEN
description The present invention relates to novel metalloproteinase inhibitors having an aryloxybenzenesulfonamide moiety and a carbamoylphosphonic acid moiety, to pharmaceutical compositions comprising them, and to their uses in the prevention and/or treatment of disease or disorder associated with MMP.
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language eng ; fre ; ger
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subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF
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