CEFDINIR ACID DOUBLE SALT AND ITS PREPARATION

The invention provides an acid double salt of cefdinir. The acid double salt is obtained by reacting cefdinir with acid and alkali metal element or ammonium (including ammonia) compound or with acid salt. The cefdinir sulfate double salt is prepared when acid or acid salt is sulfate. The cefdinir ph...

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Hauptverfasser: YE, TIANJIAN, QI, YINGBEI, ZHANG, FENGMIN, YU, BAOCHUN, YU, MEIPING, JIE, QING, QI, YOUMAO, YE, FENGQI
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creator YE, TIANJIAN
QI, YINGBEI
ZHANG, FENGMIN
YU, BAOCHUN
YU, MEIPING
JIE, QING
QI, YOUMAO
YE, FENGQI
description The invention provides an acid double salt of cefdinir. The acid double salt is obtained by reacting cefdinir with acid and alkali metal element or ammonium (including ammonia) compound or with acid salt. The cefdinir sulfate double salt is prepared when acid or acid salt is sulfate. The cefdinir phosphate double salt is prepared when acid or acid salt is phosphate. The cefdinir acid double salt of the present invention has the obvious advantages of good solubility and high bioavailability, and can be prepared into oral solid preparation or injection. The cefdinir acid double salt has the following structural general formula.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CEFDINIR ACID DOUBLE SALT AND ITS PREPARATION
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