A ENTERIC FORMULATION OF DULOXETINE AND ITS CORE AND PREPRATION METHOD

A ENTERIC FORMULATION OF DULOXETINE AND ITS CORE AND PREPRATION METHOD

An enteric formulation of duloxetine, its core and preparing method thereof are disclosed. The core comprises duloxetine or its salt and pharmaceutically acceptable excipients. The excipients include water-soluble hot melt materials selected from PEG, poloxamer, polyoxyl (40) stearate or their mixtu...

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Hauptverfasser: DING, YUNHUI, ZHENG, SIJI
Format: Patent
Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator DING, YUNHUI
ZHENG, SIJI
description An enteric formulation of duloxetine, its core and preparing method thereof are disclosed. The core comprises duloxetine or its salt and pharmaceutically acceptable excipients. The excipients include water-soluble hot melt materials selected from PEG, poloxamer, polyoxyl (40) stearate or their mixture. Based on the total weight of the core, the amount of water-soluble hot melt materials is 10%ˆ¼40% and the amount of duloxetine or its salt is 15ˆ¼60%. The core material is prepared by hot melt process. The enteric formulation comprises the core, a separating layer and an enteric layer.
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The core comprises duloxetine or its salt and pharmaceutically acceptable excipients. The excipients include water-soluble hot melt materials selected from PEG, poloxamer, polyoxyl (40) stearate or their mixture. Based on the total weight of the core, the amount of water-soluble hot melt materials is 10%ˆ¼40% and the amount of duloxetine or its salt is 15ˆ¼60%. The core material is prepared by hot melt process. 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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title A ENTERIC FORMULATION OF DULOXETINE AND ITS CORE AND PREPRATION METHOD
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