YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE
The present invention is directed to cellulytic host cells. The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol fro...
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creator | SIIKA-AHO, MATTI MCBRIDE, JOHN PENTTILA, MERJA HAU, HEIDI HANSON RICE, CHARLES STONEHOUSE, EMILY A LAGRANGE, DANIE VAN ZYL, EMILE MELLON, MARK UUSITALO, JAANA FROEHLICH, ALAN VILLARI, JEFF GHANDI, CHHAYAL BREVNOVA, ELENA FLATT, JIM DEN HAAN, RIAAN DELEAULT, KRISTEN ILMEN, MARJA ROSE, SHAUNITA RAJGARHIA, VINEET |
description | The present invention is directed to cellulytic host cells. The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol from cellulose. In addition, multiple host cells expressing different heterologous cellulases can be co-cultured together and used to produce ethanol from cellulose. Furthermore, the invention demonstrates for the first time the ability of Kluyveromyces to produce ethanol from cellulose. The yeast strains and co-cultures of yeast strains of the invention can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of saccharification and fermentation processes. |
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The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol from cellulose. In addition, multiple host cells expressing different heterologous cellulases can be co-cultured together and used to produce ethanol from cellulose. Furthermore, the invention demonstrates for the first time the ability of Kluyveromyces to produce ethanol from cellulose. 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The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol from cellulose. In addition, multiple host cells expressing different heterologous cellulases can be co-cultured together and used to produce ethanol from cellulose. Furthermore, the invention demonstrates for the first time the ability of Kluyveromyces to produce ethanol from cellulose. The yeast strains and co-cultures of yeast strains of the invention can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of saccharification and fermentation processes.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDEKAjEQANNYiPqH_YBFjNgvceMFcsmRTUAbj0PWSvTg_D8KWlhaDQzDzNX5RMgF6NhlYvbxAJZCqAGZGFzKwL6toWCkVBkYrW0we-ctFp8iYNyDo9xSLB9Rfx6Jaalm1-E2yerLhXrnxTZrGR-9TONwkbs8e-o2ZqeN1rg1fyQvFBUzGA</recordid><startdate>20130327</startdate><enddate>20130327</enddate><creator>SIIKA-AHO, MATTI</creator><creator>MCBRIDE, JOHN</creator><creator>PENTTILA, MERJA</creator><creator>HAU, HEIDI HANSON</creator><creator>RICE, CHARLES</creator><creator>STONEHOUSE, EMILY A</creator><creator>LAGRANGE, DANIE</creator><creator>VAN ZYL, EMILE</creator><creator>MELLON, MARK</creator><creator>UUSITALO, JAANA</creator><creator>FROEHLICH, ALAN</creator><creator>VILLARI, JEFF</creator><creator>GHANDI, CHHAYAL</creator><creator>BREVNOVA, ELENA</creator><creator>FLATT, JIM</creator><creator>DEN HAAN, RIAAN</creator><creator>DELEAULT, KRISTEN</creator><creator>ILMEN, MARJA</creator><creator>ROSE, SHAUNITA</creator><creator>RAJGARHIA, VINEET</creator><scope>EVB</scope></search><sort><creationdate>20130327</creationdate><title>YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE</title><author>SIIKA-AHO, MATTI ; MCBRIDE, JOHN ; PENTTILA, MERJA ; HAU, HEIDI HANSON ; RICE, CHARLES ; STONEHOUSE, EMILY A ; LAGRANGE, DANIE ; VAN ZYL, EMILE ; MELLON, MARK ; UUSITALO, JAANA ; FROEHLICH, ALAN ; VILLARI, JEFF ; GHANDI, CHHAYAL ; BREVNOVA, ELENA ; FLATT, JIM ; DEN HAAN, RIAAN ; DELEAULT, KRISTEN ; ILMEN, MARJA ; ROSE, SHAUNITA ; RAJGARHIA, VINEET</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2361311A43</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2013</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>SIIKA-AHO, MATTI</creatorcontrib><creatorcontrib>MCBRIDE, JOHN</creatorcontrib><creatorcontrib>PENTTILA, MERJA</creatorcontrib><creatorcontrib>HAU, HEIDI HANSON</creatorcontrib><creatorcontrib>RICE, CHARLES</creatorcontrib><creatorcontrib>STONEHOUSE, EMILY A</creatorcontrib><creatorcontrib>LAGRANGE, DANIE</creatorcontrib><creatorcontrib>VAN ZYL, EMILE</creatorcontrib><creatorcontrib>MELLON, MARK</creatorcontrib><creatorcontrib>UUSITALO, JAANA</creatorcontrib><creatorcontrib>FROEHLICH, ALAN</creatorcontrib><creatorcontrib>VILLARI, JEFF</creatorcontrib><creatorcontrib>GHANDI, CHHAYAL</creatorcontrib><creatorcontrib>BREVNOVA, ELENA</creatorcontrib><creatorcontrib>FLATT, JIM</creatorcontrib><creatorcontrib>DEN HAAN, RIAAN</creatorcontrib><creatorcontrib>DELEAULT, KRISTEN</creatorcontrib><creatorcontrib>ILMEN, MARJA</creatorcontrib><creatorcontrib>ROSE, SHAUNITA</creatorcontrib><creatorcontrib>RAJGARHIA, VINEET</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SIIKA-AHO, MATTI</au><au>MCBRIDE, JOHN</au><au>PENTTILA, MERJA</au><au>HAU, HEIDI HANSON</au><au>RICE, CHARLES</au><au>STONEHOUSE, EMILY A</au><au>LAGRANGE, DANIE</au><au>VAN ZYL, EMILE</au><au>MELLON, MARK</au><au>UUSITALO, JAANA</au><au>FROEHLICH, ALAN</au><au>VILLARI, JEFF</au><au>GHANDI, CHHAYAL</au><au>BREVNOVA, ELENA</au><au>FLATT, JIM</au><au>DEN HAAN, RIAAN</au><au>DELEAULT, KRISTEN</au><au>ILMEN, MARJA</au><au>ROSE, SHAUNITA</au><au>RAJGARHIA, VINEET</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE</title><date>2013-03-27</date><risdate>2013</risdate><abstract>The present invention is directed to cellulytic host cells. The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol from cellulose. In addition, multiple host cells expressing different heterologous cellulases can be co-cultured together and used to produce ethanol from cellulose. Furthermore, the invention demonstrates for the first time the ability of Kluyveromyces to produce ethanol from cellulose. The yeast strains and co-cultures of yeast strains of the invention can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of saccharification and fermentation processes.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
title | YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE |
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