COMPOUNDS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASES OF THE CNS

Inflammatory diseases in the CNS can be treated or alleviated by the administration of an oligonucleotide in an amount sufficient to reduce the influx of mononuclear cells to the central nervous system by down-regulating the expression of at least one cell surface marker. For example multiple sclero...

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Hauptverfasser: ZARGARI, AREZOU, VON STEIN, OLIVER, BANDHOLTZ, LISA CHARLOTTA, AXELSSON, LARS-GÖRAN, GIELEN, ALEXANDER
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creator ZARGARI, AREZOU
VON STEIN, OLIVER
BANDHOLTZ, LISA CHARLOTTA
AXELSSON, LARS-GÖRAN
GIELEN, ALEXANDER
description Inflammatory diseases in the CNS can be treated or alleviated by the administration of an oligonucleotide in an amount sufficient to reduce the influx of mononuclear cells to the central nervous system by down-regulating the expression of at least one cell surface marker. For example multiple sclerosis can be treated or at least alleviated, by the administration of an oligonucleotide in a dose effective to inhibit or reduce the influx of mononuclear and/or autoaggressive cells to the central nervous system. The oligonucleotide can be used alone, or in combination with other treatment strategies.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title COMPOUNDS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASES OF THE CNS
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