STABLE AQUEOUS FORMULATIONS OF WATER INSOLUBLE OR POORLY SOLUBLE DRUGS

A novel pharmaceutical formulation and process for manufacturing an aqueous based formulation of drugs with low or no water solubility. The drug is combined with the inclusion carrier cyclodextrin, eliminating the need for using organic solvents, to combine the drug, in an aqueous solution of cyclod...

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Hauptverfasser: LO DUCA BLOMBERG, JESSICA, ANDREA, CHILTON, ANTHONY, STEPHEN, INGALLINERA, THOMAS, SAMUEL
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Sprache:eng ; fre ; ger
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creator LO DUCA BLOMBERG, JESSICA, ANDREA
CHILTON, ANTHONY, STEPHEN
INGALLINERA, THOMAS, SAMUEL
description A novel pharmaceutical formulation and process for manufacturing an aqueous based formulation of drugs with low or no water solubility. The drug is combined with the inclusion carrier cyclodextrin, eliminating the need for using organic solvents, to combine the drug, in an aqueous solution of cyclodextrin and heating the resulting mixture above its melting point and allowing the drug to be drawn into the cyclodextrin.
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language eng ; fre ; ger
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subjects CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NANOTECHNOLOGY
ORGANIC MACROMOLECULAR COMPOUNDS
PERFORMING OPERATIONS
POLYSACCHARIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
THEIR PREPARATION OR CHEMICAL WORKING-UP
TRANSPORTING
title STABLE AQUEOUS FORMULATIONS OF WATER INSOLUBLE OR POORLY SOLUBLE DRUGS
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