TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS

Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases.

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Hauptverfasser: RAST, BRYSON, DELISLE, ROBERT KIRK, MARMSATER, FREDRIK, P, DAVIS, T. GREGG, TOPALOV, GEORGE T, JACKSON, LEILA, J, WRIGHT, A. DALE, CELESTE, LAURA L, LYSSIKATOS, JOSEPH, P, MUNSON, MARK, C, ZHAO, QIAN, KALLAN, NICHOLAS C, PHENEGER, JED, HICKEN, ERIK, JAMES, GROSS, STEFAN, D, ROBINSON, JOHN, E, GRESCHUK, JULIE MARIE, ALLEN, SHELLEY, SCHLACHTER, STEPHEN T
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creator RAST, BRYSON
DELISLE, ROBERT KIRK
MARMSATER, FREDRIK, P
DAVIS, T. GREGG
TOPALOV, GEORGE T
JACKSON, LEILA, J
WRIGHT, A. DALE
CELESTE, LAURA L
LYSSIKATOS, JOSEPH, P
MUNSON, MARK, C
ZHAO, QIAN
KALLAN, NICHOLAS C
PHENEGER, JED
HICKEN, ERIK, JAMES
GROSS, STEFAN, D
ROBINSON, JOHN, E
GRESCHUK, JULIE MARIE
ALLEN, SHELLEY
SCHLACHTER, STEPHEN T
description Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS
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