2-(morpholin-4-yl)pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer
Compounds having formula I are provided where the variables have the values described herein. Pharmaceutical formulations include the compounds or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier and combinations with other agents. These compounds are phosphotidyli...
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creator | PECCHI, SABINA RENHOWE, PAUL A NUSS, JOHN M |
description | Compounds having formula I are provided where the variables have the values described herein.
Pharmaceutical formulations include the compounds or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier and combinations with other agents. These compounds are phosphotidylinositol 3-kinase (PI3K) inhibitors. |
format | Patent |
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Pharmaceutical formulations include the compounds or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier and combinations with other agents. These compounds are phosphotidylinositol 3-kinase (PI3K) inhibitors.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi7EOwjAQQ7swIOAfbmyHDG0Q6gwqgq0DexXaq3oivUTJIdS_JyA-gMGy7Gevs1el8tkFPzlLrPZqsYVfAs00EGMEEyGhmCQ0LGniIomzkLfXArR6EJuIQDzRPfUhHXgAmZACPL_gE0ACGpmRBdwIveEewzZbjcZG3P18k8G5uZ0uCr3rMHrTI6N0TVvp8lDr8ljqPyZvRHZEdQ</recordid><startdate>20130306</startdate><enddate>20130306</enddate><creator>PECCHI, SABINA</creator><creator>RENHOWE, PAUL A</creator><creator>NUSS, JOHN M</creator><scope>EVB</scope></search><sort><creationdate>20130306</creationdate><title>2-(morpholin-4-yl)pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer</title><author>PECCHI, SABINA ; RENHOWE, PAUL A ; NUSS, JOHN M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2316831B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2013</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>PECCHI, SABINA</creatorcontrib><creatorcontrib>RENHOWE, PAUL A</creatorcontrib><creatorcontrib>NUSS, JOHN M</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PECCHI, SABINA</au><au>RENHOWE, PAUL A</au><au>NUSS, JOHN M</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>2-(morpholin-4-yl)pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer</title><date>2013-03-06</date><risdate>2013</risdate><abstract>Compounds having formula I are provided where the variables have the values described herein.
Pharmaceutical formulations include the compounds or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier and combinations with other agents. These compounds are phosphotidylinositol 3-kinase (PI3K) inhibitors.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | 2-(morpholin-4-yl)pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer |
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