Macrocyclic inhibitors of Hepatitis C virus replication
The embodiments provide compounds of the general Formulae I through general Formula VIII, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | WANG, BIN LIU, WEIDONG ANDREWS, STEVEN W JIANG, YUTONG MARTIN, PIERRE SAMMAKIA, TAREK KENNEDY, APRIL KAUS, ROBERT NICHOLS, PAUL SCHUMACHER, ANDREAS BARNETT, BRADLEY R LYON, MICHAEL EARY, TODD C SEIWERT, SCOTT D KERCHER, TIMOTHY BLATT, LAWRENCE M |
| description | The embodiments provide compounds of the general Formulae I through general Formula VIII, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP2305698A3</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP2305698A3</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP2305698A33</originalsourceid><addsrcrecordid>eNrjZDD3TUwuyk-uTM7JTFbIzMvITMosyS8qVshPU_BILUgsySzJLFZwVijLLCotVihKLQAqAwrm5_EwsKYl5hSn8kJpbgYFN9cQZw_d1IL8-NTigsTk1LzUknjXACNjA1MzSwtHY2MilAAAkFotxg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Macrocyclic inhibitors of Hepatitis C virus replication</title><source>esp@cenet</source><creator>WANG, BIN ; LIU, WEIDONG ; ANDREWS, STEVEN W ; JIANG, YUTONG ; MARTIN, PIERRE ; SAMMAKIA, TAREK ; KENNEDY, APRIL ; KAUS, ROBERT ; NICHOLS, PAUL ; SCHUMACHER, ANDREAS ; BARNETT, BRADLEY R ; LYON, MICHAEL ; EARY, TODD C ; SEIWERT, SCOTT D ; KERCHER, TIMOTHY ; BLATT, LAWRENCE M</creator><creatorcontrib>WANG, BIN ; LIU, WEIDONG ; ANDREWS, STEVEN W ; JIANG, YUTONG ; MARTIN, PIERRE ; SAMMAKIA, TAREK ; KENNEDY, APRIL ; KAUS, ROBERT ; NICHOLS, PAUL ; SCHUMACHER, ANDREAS ; BARNETT, BRADLEY R ; LYON, MICHAEL ; EARY, TODD C ; SEIWERT, SCOTT D ; KERCHER, TIMOTHY ; BLATT, LAWRENCE M</creatorcontrib><description>The embodiments provide compounds of the general Formulae I through general Formula VIII, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.</description><language>eng ; fre ; ger</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110727&DB=EPODOC&CC=EP&NR=2305698A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110727&DB=EPODOC&CC=EP&NR=2305698A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WANG, BIN</creatorcontrib><creatorcontrib>LIU, WEIDONG</creatorcontrib><creatorcontrib>ANDREWS, STEVEN W</creatorcontrib><creatorcontrib>JIANG, YUTONG</creatorcontrib><creatorcontrib>MARTIN, PIERRE</creatorcontrib><creatorcontrib>SAMMAKIA, TAREK</creatorcontrib><creatorcontrib>KENNEDY, APRIL</creatorcontrib><creatorcontrib>KAUS, ROBERT</creatorcontrib><creatorcontrib>NICHOLS, PAUL</creatorcontrib><creatorcontrib>SCHUMACHER, ANDREAS</creatorcontrib><creatorcontrib>BARNETT, BRADLEY R</creatorcontrib><creatorcontrib>LYON, MICHAEL</creatorcontrib><creatorcontrib>EARY, TODD C</creatorcontrib><creatorcontrib>SEIWERT, SCOTT D</creatorcontrib><creatorcontrib>KERCHER, TIMOTHY</creatorcontrib><creatorcontrib>BLATT, LAWRENCE M</creatorcontrib><title>Macrocyclic inhibitors of Hepatitis C virus replication</title><description>The embodiments provide compounds of the general Formulae I through general Formula VIII, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDD3TUwuyk-uTM7JTFbIzMvITMosyS8qVshPU_BILUgsySzJLFZwVijLLCotVihKLQAqAwrm5_EwsKYl5hSn8kJpbgYFN9cQZw_d1IL8-NTigsTk1LzUknjXACNjA1MzSwtHY2MilAAAkFotxg</recordid><startdate>20110727</startdate><enddate>20110727</enddate><creator>WANG, BIN</creator><creator>LIU, WEIDONG</creator><creator>ANDREWS, STEVEN W</creator><creator>JIANG, YUTONG</creator><creator>MARTIN, PIERRE</creator><creator>SAMMAKIA, TAREK</creator><creator>KENNEDY, APRIL</creator><creator>KAUS, ROBERT</creator><creator>NICHOLS, PAUL</creator><creator>SCHUMACHER, ANDREAS</creator><creator>BARNETT, BRADLEY R</creator><creator>LYON, MICHAEL</creator><creator>EARY, TODD C</creator><creator>SEIWERT, SCOTT D</creator><creator>KERCHER, TIMOTHY</creator><creator>BLATT, LAWRENCE M</creator><scope>EVB</scope></search><sort><creationdate>20110727</creationdate><title>Macrocyclic inhibitors of Hepatitis C virus replication</title><author>WANG, BIN ; LIU, WEIDONG ; ANDREWS, STEVEN W ; JIANG, YUTONG ; MARTIN, PIERRE ; SAMMAKIA, TAREK ; KENNEDY, APRIL ; KAUS, ROBERT ; NICHOLS, PAUL ; SCHUMACHER, ANDREAS ; BARNETT, BRADLEY R ; LYON, MICHAEL ; EARY, TODD C ; SEIWERT, SCOTT D ; KERCHER, TIMOTHY ; BLATT, LAWRENCE M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2305698A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2011</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>WANG, BIN</creatorcontrib><creatorcontrib>LIU, WEIDONG</creatorcontrib><creatorcontrib>ANDREWS, STEVEN W</creatorcontrib><creatorcontrib>JIANG, YUTONG</creatorcontrib><creatorcontrib>MARTIN, PIERRE</creatorcontrib><creatorcontrib>SAMMAKIA, TAREK</creatorcontrib><creatorcontrib>KENNEDY, APRIL</creatorcontrib><creatorcontrib>KAUS, ROBERT</creatorcontrib><creatorcontrib>NICHOLS, PAUL</creatorcontrib><creatorcontrib>SCHUMACHER, ANDREAS</creatorcontrib><creatorcontrib>BARNETT, BRADLEY R</creatorcontrib><creatorcontrib>LYON, MICHAEL</creatorcontrib><creatorcontrib>EARY, TODD C</creatorcontrib><creatorcontrib>SEIWERT, SCOTT D</creatorcontrib><creatorcontrib>KERCHER, TIMOTHY</creatorcontrib><creatorcontrib>BLATT, LAWRENCE M</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WANG, BIN</au><au>LIU, WEIDONG</au><au>ANDREWS, STEVEN W</au><au>JIANG, YUTONG</au><au>MARTIN, PIERRE</au><au>SAMMAKIA, TAREK</au><au>KENNEDY, APRIL</au><au>KAUS, ROBERT</au><au>NICHOLS, PAUL</au><au>SCHUMACHER, ANDREAS</au><au>BARNETT, BRADLEY R</au><au>LYON, MICHAEL</au><au>EARY, TODD C</au><au>SEIWERT, SCOTT D</au><au>KERCHER, TIMOTHY</au><au>BLATT, LAWRENCE M</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Macrocyclic inhibitors of Hepatitis C virus replication</title><date>2011-07-27</date><risdate>2011</risdate><abstract>The embodiments provide compounds of the general Formulae I through general Formula VIII, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP2305698A3 |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Macrocyclic inhibitors of Hepatitis C virus replication |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T05%3A51%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=WANG,%20BIN&rft.date=2011-07-27&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP2305698A3%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |