STABLE TOPICAL FORMULATION COMPRISING VORICONAZOLE

STABLE TOPICAL FORMULATION COMPRISING VORICONAZOLE

The present invention relates to a stable topical formulation comprising an effective amount of voriconazole or its pharmaceutically acceptable salt, and at least a pharmaceutical carrier; a process for preparing the same and use of such formulation for the treatment of local or non-systemic fungal...

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Hauptverfasser: DHUPPAD, ULHAS, RAMESHCHANDRA, BASA, SHRADHANJALI, KOTWAL, RUPESH, SUBHASHCHANDRA, SOMNATHE, NITIN, DASHRATHRAO, KHACHANE, VASANT, SITARAM, SATPUTE, RAVINDRA, MORESHWAR, MAHAJAN, NARAYAN, TUKARAM, BHAMRE, NITIN, BABULAL
Format: Patent
Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator DHUPPAD, ULHAS, RAMESHCHANDRA
BASA, SHRADHANJALI
KOTWAL, RUPESH, SUBHASHCHANDRA
SOMNATHE, NITIN, DASHRATHRAO
KHACHANE, VASANT, SITARAM
SATPUTE, RAVINDRA, MORESHWAR
MAHAJAN, NARAYAN, TUKARAM
BHAMRE, NITIN, BABULAL
description The present invention relates to a stable topical formulation comprising an effective amount of voriconazole or its pharmaceutically acceptable salt, and at least a pharmaceutical carrier; a process for preparing the same and use of such formulation for the treatment of local or non-systemic fungal infections in a subject. In particular, the present invention relates to a stable topical formulation exhibiting a storage stability at a temperature of about 40° C. and a relative humidity of about 75% for a period of at least 3 months, and contains not more than 9% w/w total impurities (based on total weight of the formulation) formed upon storage.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title STABLE TOPICAL FORMULATION COMPRISING VORICONAZOLE
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