NOVEL HETEROCYCLIC COMPOUNDS AND USES THEROF

Novel imidazole compounds of the general formula are disclosed, wherein R1 and R2 comprise heteroaryl groups. These compounds and compositions containing them are useful in methods to treat Raf kinase-mediated disorders such as cancer.

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Hauptverfasser: SMITH, AARON, XU, YONGJIN, ZHANG, QIONG, JIN, JEFF, MACHAJEWSKI, TIMOTHY, D, SHAFER, CYNTHIA, M, RENHOWE, PAUL, A, SENDZIK, MARTIN, POON, DANIEL, ANTONIOS-MCCREA, WILLIAM, R, MCKENNA, MAUREEN, HUANG, ZILIN
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creator SMITH, AARON
XU, YONGJIN
ZHANG, QIONG
JIN, JEFF
MACHAJEWSKI, TIMOTHY, D
SHAFER, CYNTHIA, M
RENHOWE, PAUL, A
SENDZIK, MARTIN
POON, DANIEL
ANTONIOS-MCCREA, WILLIAM, R
MCKENNA, MAUREEN
HUANG, ZILIN
description Novel imidazole compounds of the general formula are disclosed, wherein R1 and R2 comprise heteroaryl groups. These compounds and compositions containing them are useful in methods to treat Raf kinase-mediated disorders such as cancer.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title NOVEL HETEROCYCLIC COMPOUNDS AND USES THEROF
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