Pharmaceutical compositions based on anticholinergically effective compounds and beta-mimetics
A new pharmaceutical composition contains an anticholinergic agent (I) and a beta -mimetic agent (II). An independent claim is included for the preparation of the composition, by mixing and formulating (I), (II) and optionally further auxiliaries, using conventional methods. ACTIVITY : Antiasthmatic...
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creator | REICHL, RICHARD PAIRET, MICHEL WALLAND, ALEXANDER BOZUNG, KARLHEINZ |
description | A new pharmaceutical composition contains an anticholinergic agent (I) and a beta -mimetic agent (II). An independent claim is included for the preparation of the composition, by mixing and formulating (I), (II) and optionally further auxiliaries, using conventional methods. ACTIVITY : Antiasthmatic; In tests against acetyl choline-induced bronchospasm in narcotized dogs, the reduction of bronchial resistance 0.5-3 hours after administration of test drugs by inhalation was ca. 10 % using 3 mu g formoterol, ca. 30 % using 3 mu g tiotropium bromide and ca. 85 % using a combination of 3 mu g formoterol and 3 mu g tiotropium bromide. MECHANISM OF ACTION : Anticholinergic; beta -mimetic. |
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An independent claim is included for the preparation of the composition, by mixing and formulating (I), (II) and optionally further auxiliaries, using conventional methods. ACTIVITY : Antiasthmatic; In tests against acetyl choline-induced bronchospasm in narcotized dogs, the reduction of bronchial resistance 0.5-3 hours after administration of test drugs by inhalation was ca. 10 % using 3 mu g formoterol, ca. 30 % using 3 mu g tiotropium bromide and ca. 85 % using a combination of 3 mu g formoterol and 3 mu g tiotropium bromide. 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An independent claim is included for the preparation of the composition, by mixing and formulating (I), (II) and optionally further auxiliaries, using conventional methods. ACTIVITY : Antiasthmatic; In tests against acetyl choline-induced bronchospasm in narcotized dogs, the reduction of bronchial resistance 0.5-3 hours after administration of test drugs by inhalation was ca. 10 % using 3 mu g formoterol, ca. 30 % using 3 mu g tiotropium bromide and ca. 85 % using a combination of 3 mu g formoterol and 3 mu g tiotropium bromide. 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An independent claim is included for the preparation of the composition, by mixing and formulating (I), (II) and optionally further auxiliaries, using conventional methods. ACTIVITY : Antiasthmatic; In tests against acetyl choline-induced bronchospasm in narcotized dogs, the reduction of bronchial resistance 0.5-3 hours after administration of test drugs by inhalation was ca. 10 % using 3 mu g formoterol, ca. 30 % using 3 mu g tiotropium bromide and ca. 85 % using a combination of 3 mu g formoterol and 3 mu g tiotropium bromide. MECHANISM OF ACTION : Anticholinergic; beta -mimetic.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
title | Pharmaceutical compositions based on anticholinergically effective compounds and beta-mimetics |
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