Pharmaceutical compositions based on anticholinergically effective compounds and beta-mimetics

A new pharmaceutical composition contains an anticholinergic agent (I) and a beta -mimetic agent (II). An independent claim is included for the preparation of the composition, by mixing and formulating (I), (II) and optionally further auxiliaries, using conventional methods. ACTIVITY : Antiasthmatic...

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Hauptverfasser: REICHL, RICHARD, PAIRET, MICHEL, WALLAND, ALEXANDER, BOZUNG, KARLHEINZ
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creator REICHL, RICHARD
PAIRET, MICHEL
WALLAND, ALEXANDER
BOZUNG, KARLHEINZ
description A new pharmaceutical composition contains an anticholinergic agent (I) and a beta -mimetic agent (II). An independent claim is included for the preparation of the composition, by mixing and formulating (I), (II) and optionally further auxiliaries, using conventional methods. ACTIVITY : Antiasthmatic; In tests against acetyl choline-induced bronchospasm in narcotized dogs, the reduction of bronchial resistance 0.5-3 hours after administration of test drugs by inhalation was ca. 10 % using 3 mu g formoterol, ca. 30 % using 3 mu g tiotropium bromide and ca. 85 % using a combination of 3 mu g formoterol and 3 mu g tiotropium bromide. MECHANISM OF ACTION : Anticholinergic; beta -mimetic.
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language eng ; fre ; ger
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Pharmaceutical compositions based on anticholinergically effective compounds and beta-mimetics
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