Compositions for treating cancer

Liposome-encapsulated vincristine is provided for treating a cancer such as a lymphoma, leukaemia or myeloma and especially non-Hodgkin's Lymphoma or Acute Lymphocytic Leukaemia. The liposomes comprise sphingomyelin and cholesterol in a ratio between 75/25 (mol % sphingomyelin/mol % cholesterol...

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Hauptverfasser: BURGE, CLIVE, T., R, WEBB, MURRAY, S, LOGAN, PATRICIA, M, CABANILLAS, FERNANDO, GOLDIE, JAMES, H, MAYER, LAWRENCE, D, SARRIS, ANDREAS, H
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creator BURGE, CLIVE, T., R
WEBB, MURRAY, S
LOGAN, PATRICIA, M
CABANILLAS, FERNANDO
GOLDIE, JAMES, H
MAYER, LAWRENCE, D
SARRIS, ANDREAS, H
description Liposome-encapsulated vincristine is provided for treating a cancer such as a lymphoma, leukaemia or myeloma and especially non-Hodgkin's Lymphoma or Acute Lymphocytic Leukaemia. The liposomes comprise sphingomyelin and cholesterol in a ratio between 75/25 (mol % sphingomyelin/mol % cholesterol) and 50/50 (mol % sphingomyelin/mol % cholesterol) and vincristine at a concentration of 0.1 to 0.5 mg/ml.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Compositions for treating cancer
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