TREATMENT OF COLON DISEASES OR PREVENTION OF COLORECTAL CARCINOMA WITH IMIDAZOQUINOLINE DERIVATIVES

The invention relates to treating colorectal polyps and precancercerous colorectal changes by topical administration of immunomodulating drugs of the imidazoquinoline family, such as imiquimod (1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine), resiquimod (4-amino-α,α-dimethyl-2-ethoxymethyl-1H-...

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Bibliographische Detailangaben
Hauptverfasser: MAUS, JOACHIM, SZELENYI, ISTVAN, PETZOLD, URSULA
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to treating colorectal polyps and precancercerous colorectal changes by topical administration of immunomodulating drugs of the imidazoquinoline family, such as imiquimod (1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine), resiquimod (4-amino-α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol), sotirimod (2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine).