PEPTIDYL NITRILES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE I INHIBITORS

The present invention provides compounds of formula (I) in which n, y, X1, X2, A, B, R1, R2, R3, R4 and R5 are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.

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Hauptverfasser: STEIN, LINDA, ANNE, FURBER, MARK, SANGANEE, HITESH, JAYANTILAL, LUCKHURST, CHRISTOPHER, ANDREW, CAGE, PETER, ALAN
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Sprache:eng ; fre ; ger
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creator STEIN, LINDA, ANNE
FURBER, MARK
SANGANEE, HITESH, JAYANTILAL
LUCKHURST, CHRISTOPHER, ANDREW
CAGE, PETER, ALAN
description The present invention provides compounds of formula (I) in which n, y, X1, X2, A, B, R1, R2, R3, R4 and R5 are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PEPTIDYL NITRILES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE I INHIBITORS
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