Riluzole aqueous suspensions

Physically and chemically stable aqueous suspensions of riluzole are disclosed together with the manufacturing methods thereof. Such aqueous suspensions comprise riluzole in particle form and at least a wetting agent, preferably a surfactant. Riluzole is in amounts from about 0.1 % to about 20% w/v...

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Hauptverfasser: ADAMI, MARCO, ARTICO, ROBERTA, BARBARESCHI, DANIELE, MASCAGNI, PAOLO, MOSCOSO, JAIME, OLDONI, TIZIANO
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creator ADAMI, MARCO
ARTICO, ROBERTA
BARBARESCHI, DANIELE
MASCAGNI, PAOLO
MOSCOSO, JAIME
OLDONI, TIZIANO
description Physically and chemically stable aqueous suspensions of riluzole are disclosed together with the manufacturing methods thereof. Such aqueous suspensions comprise riluzole in particle form and at least a wetting agent, preferably a surfactant. Riluzole is in amounts from about 0.1 % to about 20% w/v and has an average particle size lower than 200 µm; such suspensions are devoided of the known local (mouth) anaesthetic effects of riluzole.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Riluzole aqueous suspensions
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