ANTI-FACTOR XI MONOCLONAL ANTIBODIES AND METHODS OF USE THEREOF

The present invention relates to compositions and methods for inhibiting thrombosis without compromising hemostasis. Compositions include anti-factor XI monoclonal antibodies (aXIMabs) capable of binding to an epitope on the heavy chain of human FXI, particularly the A3 domain of the heavy chain of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GRUBER, ANDRAS, TUCKER, ERIK, IAN, HANSON, STEPHEN, RAYMOND, GAILANI, DAVID
Format: Patent
Sprache:eng ; fre ; ger
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