THERAPEUTIC AGENT FOR OVERACTIVE BLADDER

An object of the present invention is to find a novel pharmacological action of a urea compound having a structure represented by the general formula [I]. The urea compound having a structure represented by the general formula [I] or a salt thereof has an excellent therapeutic effect on a TRPV1-medi...

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Hauptverfasser: TSUJI, FUMIO, SEKI, IWAO, SASANO, MINORU, OKI, KENJI, MURAI, MASAAKI, SETOGUCHI, CHIKAKO
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creator TSUJI, FUMIO
SEKI, IWAO
SASANO, MINORU
OKI, KENJI
MURAI, MASAAKI
SETOGUCHI, CHIKAKO
description An object of the present invention is to find a novel pharmacological action of a urea compound having a structure represented by the general formula [I]. The urea compound having a structure represented by the general formula [I] or a salt thereof has an excellent therapeutic effect on a TRPV1-mediated disease. In the formula, A represents a lower alkylene group or a lower alkenylene group; R 1 represents a hydrogen atom, an alkyl group which may have a substituent or an alkenyl group which may have a substituent; and R 2 and R 3 are the same or different and represent a hydrogen atom or a lower alkyl group which may be substituted by a monocyclic cycloalkyl group, a polycyclic cycloalkyl group, or an aryl group.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title THERAPEUTIC AGENT FOR OVERACTIVE BLADDER
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