Method for predicting the response to a treatment with a HER dimerization inhibitor
The invention is related to a method of predicting the response to a treatment with a HER dimerization inhibitor in a patient comprising the steps of assessing a marker gene or a combination of marker genes selected from the group consisting of an epidermal growth factor, a transforming growth facto...
Gespeichert in:
Hauptverfasser: | , , |
---|---|
Format: | Patent |
Sprache: | eng ; fre ; ger |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | STRAUSS, ANDREAS ZUGMAIER, GERHARD MOECKS, JOACHIM |
description | The invention is related to a method of predicting the response to a treatment with a HER dimerization inhibitor in a patient comprising the steps of assessing a marker gene or a combination of marker genes selected from the group consisting of an epidermal growth factor, a transforming growth factor alpha and a HER2 marker gene or a combination of marker genes comprising an amphiregulin marker gene and a marker gene selected from an epidermal growth factor, a transforming growth factor alpha and a HER2 marker gene in a biological sample from the patient and predicting the response to the treatment with the HER dimerization inhibitor in the patient by evaluating the results of the first step. Further uses and methods wherein these markers are used are disclosed. |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP2196547B1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP2196547B1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP2196547B13</originalsourceid><addsrcrecordid>eNqNjDsKwkAQQLexEPUOcwGL-CWtspJGELUPa3biDpiZZXZA8PSm8ABWDx6PN3W3M1qSCL0oZMVInRE_wRKCYsnCBcEEAphisAHZ4E2WRtH4K0QaUOkTjISBONGDTHTuJn14FVz8OHNw8vdjs8Qs7TgNHTJa6y-rqt5tN_tDtf4j-QLDmjfU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Method for predicting the response to a treatment with a HER dimerization inhibitor</title><source>esp@cenet</source><creator>STRAUSS, ANDREAS ; ZUGMAIER, GERHARD ; MOECKS, JOACHIM</creator><creatorcontrib>STRAUSS, ANDREAS ; ZUGMAIER, GERHARD ; MOECKS, JOACHIM</creatorcontrib><description>The invention is related to a method of predicting the response to a treatment with a HER dimerization inhibitor in a patient comprising the steps of assessing a marker gene or a combination of marker genes selected from the group consisting of an epidermal growth factor, a transforming growth factor alpha and a HER2 marker gene or a combination of marker genes comprising an amphiregulin marker gene and a marker gene selected from an epidermal growth factor, a transforming growth factor alpha and a HER2 marker gene in a biological sample from the patient and predicting the response to the treatment with the HER dimerization inhibitor in the patient by evaluating the results of the first step. Further uses and methods wherein these markers are used are disclosed.</description><language>eng ; fre ; ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PHYSICS ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111228&DB=EPODOC&CC=EP&NR=2196547B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111228&DB=EPODOC&CC=EP&NR=2196547B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>STRAUSS, ANDREAS</creatorcontrib><creatorcontrib>ZUGMAIER, GERHARD</creatorcontrib><creatorcontrib>MOECKS, JOACHIM</creatorcontrib><title>Method for predicting the response to a treatment with a HER dimerization inhibitor</title><description>The invention is related to a method of predicting the response to a treatment with a HER dimerization inhibitor in a patient comprising the steps of assessing a marker gene or a combination of marker genes selected from the group consisting of an epidermal growth factor, a transforming growth factor alpha and a HER2 marker gene or a combination of marker genes comprising an amphiregulin marker gene and a marker gene selected from an epidermal growth factor, a transforming growth factor alpha and a HER2 marker gene in a biological sample from the patient and predicting the response to the treatment with the HER dimerization inhibitor in the patient by evaluating the results of the first step. Further uses and methods wherein these markers are used are disclosed.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PHYSICS</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDsKwkAQQLexEPUOcwGL-CWtspJGELUPa3biDpiZZXZA8PSm8ABWDx6PN3W3M1qSCL0oZMVInRE_wRKCYsnCBcEEAphisAHZ4E2WRtH4K0QaUOkTjISBONGDTHTuJn14FVz8OHNw8vdjs8Qs7TgNHTJa6y-rqt5tN_tDtf4j-QLDmjfU</recordid><startdate>20111228</startdate><enddate>20111228</enddate><creator>STRAUSS, ANDREAS</creator><creator>ZUGMAIER, GERHARD</creator><creator>MOECKS, JOACHIM</creator><scope>EVB</scope></search><sort><creationdate>20111228</creationdate><title>Method for predicting the response to a treatment with a HER dimerization inhibitor</title><author>STRAUSS, ANDREAS ; ZUGMAIER, GERHARD ; MOECKS, JOACHIM</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2196547B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2011</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PHYSICS</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>STRAUSS, ANDREAS</creatorcontrib><creatorcontrib>ZUGMAIER, GERHARD</creatorcontrib><creatorcontrib>MOECKS, JOACHIM</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>STRAUSS, ANDREAS</au><au>ZUGMAIER, GERHARD</au><au>MOECKS, JOACHIM</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Method for predicting the response to a treatment with a HER dimerization inhibitor</title><date>2011-12-28</date><risdate>2011</risdate><abstract>The invention is related to a method of predicting the response to a treatment with a HER dimerization inhibitor in a patient comprising the steps of assessing a marker gene or a combination of marker genes selected from the group consisting of an epidermal growth factor, a transforming growth factor alpha and a HER2 marker gene or a combination of marker genes comprising an amphiregulin marker gene and a marker gene selected from an epidermal growth factor, a transforming growth factor alpha and a HER2 marker gene in a biological sample from the patient and predicting the response to the treatment with the HER dimerization inhibitor in the patient by evaluating the results of the first step. Further uses and methods wherein these markers are used are disclosed.</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng ; fre ; ger |
recordid | cdi_epo_espacenet_EP2196547B1 |
source | esp@cenet |
subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE |
title | Method for predicting the response to a treatment with a HER dimerization inhibitor |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T08%3A52%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=STRAUSS,%20ANDREAS&rft.date=2011-12-28&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP2196547B1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |