Modulating responsiveness to steroids

The present invention makes it possible to enhance steroid efficacy in a steroid refractory patient afflicted with an inflammatory condition not responding or responding poorly or inadequately to anti-inflammatory treatment, by administering an effective to said patient amount of an oligonucleotide...

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Hauptverfasser: LOEFBERG, ROBERT, VON STEIN, OLIVER, ZARGARI, AREZOU, BANDHOLTZ, LISA CHARLOTTA, SPIIK, ANN-KRISTIN
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creator LOEFBERG, ROBERT
VON STEIN, OLIVER
ZARGARI, AREZOU
BANDHOLTZ, LISA CHARLOTTA
SPIIK, ANN-KRISTIN
description The present invention makes it possible to enhance steroid efficacy in a steroid refractory patient afflicted with an inflammatory condition not responding or responding poorly or inadequately to anti-inflammatory treatment, by administering an effective to said patient amount of an oligonucleotide comprising the sequence TTCGT and having a total length of up to 100 nucleotides. The invention also encompasses the use of said oligonucleotide for the manufacture of pharmaceuticals.
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language eng ; fre ; ger
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Modulating responsiveness to steroids
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