PHENYL AMINO PYRIMIDINE COMPOUNDS AND USES THEREOF

The present invention relates to phenyl amino pyrimidine compounds which are inhibitors of protein kinases including JAK kinases. In particular the compounds are selective for JAK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inf...

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Hauptverfasser: DONOHUE, ANDREW CRAIG, WILKS, ANDREW FREDERICK, BURNS, CHRISTOPHER JOHN, NGUYEN, THAO LIEN THI, FEUTRILL, JOHN THOMAS, ZENG, JUN
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creator DONOHUE, ANDREW CRAIG
WILKS, ANDREW FREDERICK
BURNS, CHRISTOPHER JOHN
NGUYEN, THAO LIEN THI
FEUTRILL, JOHN THOMAS
ZENG, JUN
description The present invention relates to phenyl amino pyrimidine compounds which are inhibitors of protein kinases including JAK kinases. In particular the compounds are selective for JAK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PHENYL AMINO PYRIMIDINE COMPOUNDS AND USES THEREOF
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