Stereoselective alkylation of chiral 2-methyl-4 protected piperazines

The invention relates to a process for preparing 4-trifluoromethyl methoxyacetophenone comprising: (a) reacting the compound of Formula XIII with the compound of formula XIX to form the product of formula XX: and (b) hydrolyzing the compound of formula XX to 4-trifluoromethyl methoxyacetophenone:

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Bibliographische Detailangaben
Hauptverfasser: WU, WENXUE, THIRUVENGADAM, T., K, SCHWARTZ, MARTIN, LAWRENCE, GALA, DINESH, LEE, GARY, M, TSAI, DAVID, J, ANDREWS, DAVID, R, FU, XIAOYONG, MCALLISTER, TIMOTHY, L, LIAO, HONGBIAO, MALONEY, DONAL, TANN, CHOU-HANG
Format: Patent
Sprache:eng ; fre ; ger
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