NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID
A compound that has affinity with amyloid, exhibits sufficiently rapid clearance from normal tissues, and is suppressed in toxicity such as mutagenicity is provided, which is represented by the following formula (1): or a salt thereof, wherein R 1 is a group selected from hydrogen, hydroxyl group, c...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | BOUVET, DENIS RAYMOND CHRISTOPHE STOREY, ANTHONY EAMON NAKAMURA, DAISAKU TANIFUJI, SHIGEYUKI HAYASHI, AKIO TAKASAKI, SHINYA |
| description | A compound that has affinity with amyloid, exhibits sufficiently rapid clearance from normal tissues, and is suppressed in toxicity such as mutagenicity is provided, which is represented by the following formula (1):
or a salt thereof,
wherein R 1 is a group selected from hydrogen, hydroxyl group, carboxyl group, sulfate group, amino group, nitro group, cyano group, an alkyl substituent with one to 4 carbon atoms or an alkoxy substituent with one to 4 carbon atoms; R 2 is a radioactive halogen substituent; and m is an integer of 0 to 2, and a low-toxic diagnostic agent for Alzheimer's disease comprising a compound represented by the above formula or a salt thereof is also provided. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP2042501A4</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP2042501A4</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP2042501A43</originalsourceid><addsrcrecordid>eNrjZNDy8w9z9VFw9vcN8A_1c1HwcAzz9HNXcHRz8_TzDIlUcPMPUnD0jfTx93ThYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgFGBiZGpgaGjibGRCgBAAw6JDE</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID</title><source>esp@cenet</source><creator>BOUVET, DENIS RAYMOND CHRISTOPHE ; STOREY, ANTHONY EAMON ; NAKAMURA, DAISAKU ; TANIFUJI, SHIGEYUKI ; HAYASHI, AKIO ; TAKASAKI, SHINYA</creator><creatorcontrib>BOUVET, DENIS RAYMOND CHRISTOPHE ; STOREY, ANTHONY EAMON ; NAKAMURA, DAISAKU ; TANIFUJI, SHIGEYUKI ; HAYASHI, AKIO ; TAKASAKI, SHINYA</creatorcontrib><description>A compound that has affinity with amyloid, exhibits sufficiently rapid clearance from normal tissues, and is suppressed in toxicity such as mutagenicity is provided, which is represented by the following formula (1):
or a salt thereof,
wherein R 1 is a group selected from hydrogen, hydroxyl group, carboxyl group, sulfate group, amino group, nitro group, cyano group, an alkyl substituent with one to 4 carbon atoms or an alkoxy substituent with one to 4 carbon atoms; R 2 is a radioactive halogen substituent; and m is an integer of 0 to 2, and a low-toxic diagnostic agent for Alzheimer's disease comprising a compound represented by the above formula or a salt thereof is also provided.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEASUREMENT OF NUCLEAR OR X-RADIATION ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; TESTING</subject><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20121121&DB=EPODOC&CC=EP&NR=2042501A4$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20121121&DB=EPODOC&CC=EP&NR=2042501A4$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BOUVET, DENIS RAYMOND CHRISTOPHE</creatorcontrib><creatorcontrib>STOREY, ANTHONY EAMON</creatorcontrib><creatorcontrib>NAKAMURA, DAISAKU</creatorcontrib><creatorcontrib>TANIFUJI, SHIGEYUKI</creatorcontrib><creatorcontrib>HAYASHI, AKIO</creatorcontrib><creatorcontrib>TAKASAKI, SHINYA</creatorcontrib><title>NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID</title><description>A compound that has affinity with amyloid, exhibits sufficiently rapid clearance from normal tissues, and is suppressed in toxicity such as mutagenicity is provided, which is represented by the following formula (1):
or a salt thereof,
wherein R 1 is a group selected from hydrogen, hydroxyl group, carboxyl group, sulfate group, amino group, nitro group, cyano group, an alkyl substituent with one to 4 carbon atoms or an alkoxy substituent with one to 4 carbon atoms; R 2 is a radioactive halogen substituent; and m is an integer of 0 to 2, and a low-toxic diagnostic agent for Alzheimer's disease comprising a compound represented by the above formula or a salt thereof is also provided.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEASUREMENT OF NUCLEAR OR X-RADIATION</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDy8w9z9VFw9vcN8A_1c1HwcAzz9HNXcHRz8_TzDIlUcPMPUnD0jfTx93ThYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgFGBiZGpgaGjibGRCgBAAw6JDE</recordid><startdate>20121121</startdate><enddate>20121121</enddate><creator>BOUVET, DENIS RAYMOND CHRISTOPHE</creator><creator>STOREY, ANTHONY EAMON</creator><creator>NAKAMURA, DAISAKU</creator><creator>TANIFUJI, SHIGEYUKI</creator><creator>HAYASHI, AKIO</creator><creator>TAKASAKI, SHINYA</creator><scope>EVB</scope></search><sort><creationdate>20121121</creationdate><title>NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID</title><author>BOUVET, DENIS RAYMOND CHRISTOPHE ; STOREY, ANTHONY EAMON ; NAKAMURA, DAISAKU ; TANIFUJI, SHIGEYUKI ; HAYASHI, AKIO ; TAKASAKI, SHINYA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2042501A43</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2012</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEASUREMENT OF NUCLEAR OR X-RADIATION</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>BOUVET, DENIS RAYMOND CHRISTOPHE</creatorcontrib><creatorcontrib>STOREY, ANTHONY EAMON</creatorcontrib><creatorcontrib>NAKAMURA, DAISAKU</creatorcontrib><creatorcontrib>TANIFUJI, SHIGEYUKI</creatorcontrib><creatorcontrib>HAYASHI, AKIO</creatorcontrib><creatorcontrib>TAKASAKI, SHINYA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BOUVET, DENIS RAYMOND CHRISTOPHE</au><au>STOREY, ANTHONY EAMON</au><au>NAKAMURA, DAISAKU</au><au>TANIFUJI, SHIGEYUKI</au><au>HAYASHI, AKIO</au><au>TAKASAKI, SHINYA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID</title><date>2012-11-21</date><risdate>2012</risdate><abstract>A compound that has affinity with amyloid, exhibits sufficiently rapid clearance from normal tissues, and is suppressed in toxicity such as mutagenicity is provided, which is represented by the following formula (1):
or a salt thereof,
wherein R 1 is a group selected from hydrogen, hydroxyl group, carboxyl group, sulfate group, amino group, nitro group, cyano group, an alkyl substituent with one to 4 carbon atoms or an alkoxy substituent with one to 4 carbon atoms; R 2 is a radioactive halogen substituent; and m is an integer of 0 to 2, and a low-toxic diagnostic agent for Alzheimer's disease comprising a compound represented by the above formula or a salt thereof is also provided.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP2042501A4 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEASUREMENT OF NUCLEAR OR X-RADIATION MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING |
| title | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T04%3A19%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BOUVET,%20DENIS%20RAYMOND%20CHRISTOPHE&rft.date=2012-11-21&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP2042501A4%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |