QUINOLINE COMPOUNDS AND METHODS OF USE

QUINOLINE COMPOUNDS AND METHODS OF USE

Compounds of Formula (I), and stereoisomers, geometric isomers, tautomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof, are useful for inhibiting receptor tyrosine kinases and for treating hyperproliferative disorders mediated thereby. Methods of using compounds of...

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Hauptverfasser: MARLOW, ALLISON L, KAPLAN, TOMAS, SEO, JEONGBEOB, GAUDINO, JOHN, BLAKE, JAMES, FONG, KIN CHIU, KOCH, KEVIN, BOYD, STEVEN ARMEN, TIAN, HONGQI
Format: Patent
Sprache:eng ; fre ; ger
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator MARLOW, ALLISON L
KAPLAN, TOMAS
SEO, JEONGBEOB
GAUDINO, JOHN
BLAKE, JAMES
FONG, KIN CHIU
KOCH, KEVIN
BOYD, STEVEN ARMEN
TIAN, HONGQI
description Compounds of Formula (I), and stereoisomers, geometric isomers, tautomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof, are useful for inhibiting receptor tyrosine kinases and for treating hyperproliferative disorders mediated thereby. Methods of using compounds of Formula (I), and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title QUINOLINE COMPOUNDS AND METHODS OF USE
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