Methods of administering epothilone analogs for the treatment of cancer

Formulating an epothilone analog (I) for parenteral administration, comprises: (A) dissolving the analog in tert-butanol and water; (B) primary drying at -10 - -40 EC; (C) secondary drying at 10 - 30 EC; and (D) packaging the lyophilized product in a first vial in combination with a second vial cont...

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Hauptverfasser: RAGHAVAN, KRISHNASWAMY SRINIVAS, BANDYOPADHYAH, REBANTA, MALLOY, TIMOTHY M, VARIA, SAILESH AMILAL, PANAGGIO, ANDREA
Format: Patent
Sprache:eng ; fre ; ger
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