NOVEL HIGH AFFINITY THIOPHENE-BASED AND FURAN-BASED KINASE LIGANDS

Inhibitors of cyclin dependent kinase 2, compositions including the inhibitors, and methods of using the inhibitors and inhibitor compositions are described. The inhibitors and compositions including them are useful for treating disease or disease symptoms. The invention also provides for methods of...

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Hauptverfasser: SIDDIQUI, M. ARSHAD, MCNEMAR, CHARLES, W, MAYHOOD, TODD, W, SHIPPS, GERALD W., JR, WINDSOR, WILLIAM, T, PARRY, DAVID, A, DENG, YONGQI, LEES, EMMA, M, CURRAN, PATRICK, J, ZHANG, RUMIN, ZHAO, LIANYUN
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creator SIDDIQUI, M. ARSHAD
MCNEMAR, CHARLES, W
MAYHOOD, TODD, W
SHIPPS, GERALD W., JR
WINDSOR, WILLIAM, T
PARRY, DAVID, A
DENG, YONGQI
LEES, EMMA, M
CURRAN, PATRICK, J
ZHANG, RUMIN
ZHAO, LIANYUN
description Inhibitors of cyclin dependent kinase 2, compositions including the inhibitors, and methods of using the inhibitors and inhibitor compositions are described. The inhibitors and compositions including them are useful for treating disease or disease symptoms. The invention also provides for methods of making CDK-2 inhibitor compounds, methods of inhibiting CDK-2, and methods for treating disease or disease symptoms.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title NOVEL HIGH AFFINITY THIOPHENE-BASED AND FURAN-BASED KINASE LIGANDS
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