TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, s...
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| creator | YING, WEIWEN PRZEWLOKA, TERESA CHIMMANAMADA, DINESH, U NG, HOWARD, P ZHANG, SHIJE JAMES, DAVID FOLEY, KEVIN CHAE, JUNGHYUN KOSTIK, ELENA DU, ZHENJIAN LEE, CHI-WAN BARSOUM,JAMES |
| description | The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. |
| format | Patent |
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The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140604&DB=EPODOC&CC=EP&NR=1928846B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140604&DB=EPODOC&CC=EP&NR=1928846B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YING, WEIWEN</creatorcontrib><creatorcontrib>PRZEWLOKA, TERESA</creatorcontrib><creatorcontrib>CHIMMANAMADA, DINESH, U</creatorcontrib><creatorcontrib>NG, HOWARD, P</creatorcontrib><creatorcontrib>ZHANG, SHIJE</creatorcontrib><creatorcontrib>JAMES, DAVID</creatorcontrib><creatorcontrib>FOLEY, KEVIN</creatorcontrib><creatorcontrib>CHAE, JUNGHYUN</creatorcontrib><creatorcontrib>KOSTIK, ELENA</creatorcontrib><creatorcontrib>DU, ZHENJIAN</creatorcontrib><creatorcontrib>LEE, CHI-WAN</creatorcontrib><creatorcontrib>BARSOUM,JAMES</creatorcontrib><title>TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY</title><description>The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. 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The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY |
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