VDCC GAMMA-8 ION CHANNEL

VDCC GAMMA-8 ION CHANNEL

VDCC gamma-8 polypeptides comprising the amino acid sequence shown in SEQ ID NO. 3, SEQ ID NO. 5 or SEQ ID NO: 7, and homologues, variants and derivatives thereof are provided. Nucleic acids capable of encoding VDCC gamma-8 polypeptide are also disclosed, in particular, those comprising the nucleic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: POWELL, JUSTIN, HORWOOD, JENNIFER, MARIE, SHEARDOWN, MALCOLM, DIXON, JOHN, LIU, HAIPING, BRICE, NICOLA, FOO, KOK, SIU, MALINGE, ISABELLE
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:VDCC gamma-8 polypeptides comprising the amino acid sequence shown in SEQ ID NO. 3, SEQ ID NO. 5 or SEQ ID NO: 7, and homologues, variants and derivatives thereof are provided. Nucleic acids capable of encoding VDCC gamma-8 polypeptide are also disclosed, in particular, those comprising the nucleic acid sequences shown in SEQ ID No. 1, SEQ ID No. 2, SEQ ID NO. 4 or SEQ ID NO: 6. These polypeptides and polynucleotides are implicated in mental illness and are useful in screening for therapeutic agents useful in treating mental illness.