CYCLOHEPTA(b)PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING SAME
The present invention relates to a medicine, particularly a medicine comprising a novel cyclohepta[b]pyridine-3-carbonylguanidine derivative having an inhibitory effect on an Na + /H + exchanger (NHE). There is provided a cyclohepta[b]pyridine-3-carbonylguanidine derivative represented by Formula (1...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | TAKAYANAGI, KOICHI UEMOTO, KAZUHIRO KAZAYAMA, SHIN-ICHI |
| description | The present invention relates to a medicine, particularly a medicine comprising a novel cyclohepta[b]pyridine-3-carbonylguanidine derivative having an inhibitory effect on an Na + /H + exchanger (NHE). There is provided a cyclohepta[b]pyridine-3-carbonylguanidine derivative represented by Formula (1):
wherein R 1 is a group selected from a sulfo group, a sulfoxy group, -OCONH-(CH 2 CH 2 O) n -SO 3 H and the following formulas:
R 2 represents a halogen atom, a lower alkyl group or a lower alkoxy group; and n represents an integer from 1 to 10,
or a pharmaceutically acceptable salt thereof. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP1849774B1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP1849774B1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP1849774B13</originalsourceid><addsrcrecordid>eNqNyrEKwjAQgOEuDqK-w406dCgtVMfr5WwD7SXEpNCpVImTaKG-P4L4AE4_fPzrZKSBWtOw9bi_HuzgtNLCaZ4SusrI0NYB5Wug2Okeve4ZUBTYBl2HxMFrwhasMyqQBzLiUYuWGi7Y8TZZ3afHEne_bhI4s6cmjfNrjMs83eIzvke22bE4lWVRZfkfywciTDM4</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>CYCLOHEPTA(b)PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING SAME</title><source>esp@cenet</source><creator>TAKAYANAGI, KOICHI ; UEMOTO, KAZUHIRO ; KAZAYAMA, SHIN-ICHI</creator><creatorcontrib>TAKAYANAGI, KOICHI ; UEMOTO, KAZUHIRO ; KAZAYAMA, SHIN-ICHI</creatorcontrib><description>The present invention relates to a medicine, particularly a medicine comprising a novel cyclohepta[b]pyridine-3-carbonylguanidine derivative having an inhibitory effect on an Na + /H + exchanger (NHE). There is provided a cyclohepta[b]pyridine-3-carbonylguanidine derivative represented by Formula (1):
wherein R 1 is a group selected from a sulfo group, a sulfoxy group, -OCONH-(CH 2 CH 2 O) n -SO 3 H and the following formulas:
R 2 represents a halogen atom, a lower alkyl group or a lower alkoxy group; and n represents an integer from 1 to 10,
or a pharmaceutically acceptable salt thereof.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110629&DB=EPODOC&CC=EP&NR=1849774B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110629&DB=EPODOC&CC=EP&NR=1849774B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TAKAYANAGI, KOICHI</creatorcontrib><creatorcontrib>UEMOTO, KAZUHIRO</creatorcontrib><creatorcontrib>KAZAYAMA, SHIN-ICHI</creatorcontrib><title>CYCLOHEPTA(b)PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING SAME</title><description>The present invention relates to a medicine, particularly a medicine comprising a novel cyclohepta[b]pyridine-3-carbonylguanidine derivative having an inhibitory effect on an Na + /H + exchanger (NHE). There is provided a cyclohepta[b]pyridine-3-carbonylguanidine derivative represented by Formula (1):
wherein R 1 is a group selected from a sulfo group, a sulfoxy group, -OCONH-(CH 2 CH 2 O) n -SO 3 H and the following formulas:
R 2 represents a halogen atom, a lower alkyl group or a lower alkoxy group; and n represents an integer from 1 to 10,
or a pharmaceutically acceptable salt thereof.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQgOEuDqK-w406dCgtVMfr5WwD7SXEpNCpVImTaKG-P4L4AE4_fPzrZKSBWtOw9bi_HuzgtNLCaZ4SusrI0NYB5Wug2Okeve4ZUBTYBl2HxMFrwhasMyqQBzLiUYuWGi7Y8TZZ3afHEne_bhI4s6cmjfNrjMs83eIzvke22bE4lWVRZfkfywciTDM4</recordid><startdate>20110629</startdate><enddate>20110629</enddate><creator>TAKAYANAGI, KOICHI</creator><creator>UEMOTO, KAZUHIRO</creator><creator>KAZAYAMA, SHIN-ICHI</creator><scope>EVB</scope></search><sort><creationdate>20110629</creationdate><title>CYCLOHEPTA(b)PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING SAME</title><author>TAKAYANAGI, KOICHI ; UEMOTO, KAZUHIRO ; KAZAYAMA, SHIN-ICHI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP1849774B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2011</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>TAKAYANAGI, KOICHI</creatorcontrib><creatorcontrib>UEMOTO, KAZUHIRO</creatorcontrib><creatorcontrib>KAZAYAMA, SHIN-ICHI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TAKAYANAGI, KOICHI</au><au>UEMOTO, KAZUHIRO</au><au>KAZAYAMA, SHIN-ICHI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CYCLOHEPTA(b)PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING SAME</title><date>2011-06-29</date><risdate>2011</risdate><abstract>The present invention relates to a medicine, particularly a medicine comprising a novel cyclohepta[b]pyridine-3-carbonylguanidine derivative having an inhibitory effect on an Na + /H + exchanger (NHE). There is provided a cyclohepta[b]pyridine-3-carbonylguanidine derivative represented by Formula (1):
wherein R 1 is a group selected from a sulfo group, a sulfoxy group, -OCONH-(CH 2 CH 2 O) n -SO 3 H and the following formulas:
R 2 represents a halogen atom, a lower alkyl group or a lower alkoxy group; and n represents an integer from 1 to 10,
or a pharmaceutically acceptable salt thereof.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP1849774B1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CYCLOHEPTA(b)PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING SAME |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T01%3A06%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=TAKAYANAGI,%20KOICHI&rft.date=2011-06-29&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP1849774B1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |