A PROCESS FOR PREPARATION OF IMATINIB BASE

An improved process for the preparation of imatinib base and its pharmaceutically acceptable acid addition salts by (a) reacting 2-methyl-5-nitroaniline with cyanamide in the presence of hydrochloric acid to obtain 1-(2-methyl-5-nitrophenyl)guanidine hydrochloride; (b) converting 1-(2-methyl-5-nitro...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	SAMSON-LAZINSKA, DOROTA, SZCZEPEK, WOJCIECH, KACZMAREK, LUKASZ, ZAGRODZKI, BOGDAN, SKARZYNSKI, MACIEJ, LUNIEWSKI, WOJCIECH, SZELEJEWSKI, WIESLAW
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!