AZACYCLIC COMPOUNDS AS INHBITORS OF SENSORY NEURONE SPECIFIC CHANNELS (SNS)
Compounds of the formula (I) , and pharmaceutically acceptable salts thereof , are found to be antagonists of SNS sodium channels. They are therefore useful as analgesic and neuroprotective agents. wherein: - Ar represents a phenyl ring or a 5 - to 6- membered heteroaryl group; - m is 1 , 2 or 3 .
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| creator | KNUTSEN, LARS JACOB S HUCKSTEP, MIKE BOYD, JOSEPH WILLIAM EARNSHAW, CHRISTOPHER G STOKES, STEPHEN PATIENT, LEE HAMLYN, RICHARD TICKLE, DAVID ALLART, BRIGITTE LYNCH, ROSEMARY |
| description | Compounds of the formula (I) , and pharmaceutically acceptable salts thereof , are found to be antagonists of SNS sodium channels. They are therefore useful as analgesic and neuroprotective agents. wherein: - Ar represents a phenyl ring or a 5 - to 6- membered heteroaryl group; - m is 1 , 2 or 3 . |
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They are therefore useful as analgesic and neuroprotective agents. wherein: - Ar represents a phenyl ring or a 5 - to 6- membered heteroaryl group; - m is 1 , 2 or 3 .</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | AZACYCLIC COMPOUNDS AS INHBITORS OF SENSORY NEURONE SPECIFIC CHANNELS (SNS) |
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