AZACYCLIC COMPOUNDS AS INHBITORS OF SENSORY NEURONE SPECIFIC CHANNELS (SNS)

Compounds of the formula (I) , and pharmaceutically acceptable salts thereof , are found to be antagonists of SNS sodium channels. They are therefore useful as analgesic and neuroprotective agents. wherein: - Ar represents a phenyl ring or a 5 - to 6- membered heteroaryl group; - m is 1 , 2 or 3 .

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Bibliographische Detailangaben
Hauptverfasser:	KNUTSEN, LARS JACOB S, HUCKSTEP, MIKE, BOYD, JOSEPH WILLIAM, EARNSHAW, CHRISTOPHER G, STOKES, STEPHEN, PATIENT, LEE, HAMLYN, RICHARD, TICKLE, DAVID, ALLART, BRIGITTE, LYNCH, ROSEMARY
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of the formula (I) , and pharmaceutically acceptable salts thereof , are found to be antagonists of SNS sodium channels. They are therefore useful as analgesic and neuroprotective agents. wherein: - Ar represents a phenyl ring or a 5 - to 6- membered heteroaryl group; - m is 1 , 2 or 3 .