CHROMATOGRAPHY MATRIX
The present invention relates to a chromatography ligand defined by the following formula R1-R2-N(R3)-R4-R5 wherein R1 is a substituted or non-substituted phenyl group; R2 is a hydrocarbon chain comprising 0-4 carbon atoms; R3 is a hydrocarbon chain comprising 1-3 carbon atoms; R4 is a hydrocarbon c...
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| creator | MALOISEL, Jean-Luc, Amersham Biosciences AB ENGSTRAND, Carina, Amersham Biosciences AB FORSS, Annika, Amersham Biosciences AB GLAD, Gunnar, Amersham Biosciences AB JOHANSSON, Bo-Lennart, Amersham Biosciences AB JOHANSSON, Hans J., Amersham Biosciences AB |
| description | The present invention relates to a chromatography ligand defined by the following formula R1-R2-N(R3)-R4-R5 wherein R1 is a substituted or non-substituted phenyl group; R2 is a hydrocarbon chain comprising 0-4 carbon atoms; R3 is a hydrocarbon chain comprising 1-3 carbon atoms; R4 is a hydrocarbon chain comprising 1-5 carbon atoms; and R5 is OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies. |
| format | Patent |
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The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.</description><language>eng ; fre ; ger</language><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; SEPARATION ; THEIR RELEVANT APPARATUS ; TRANSPORTING</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161207&DB=EPODOC&CC=EP&NR=1827691B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161207&DB=EPODOC&CC=EP&NR=1827691B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MALOISEL, Jean-Luc, Amersham Biosciences AB</creatorcontrib><creatorcontrib>ENGSTRAND, Carina, Amersham Biosciences AB</creatorcontrib><creatorcontrib>FORSS, Annika, Amersham Biosciences AB</creatorcontrib><creatorcontrib>GLAD, Gunnar, Amersham Biosciences AB</creatorcontrib><creatorcontrib>JOHANSSON, Bo-Lennart, Amersham Biosciences AB</creatorcontrib><creatorcontrib>JOHANSSON, Hans J., Amersham Biosciences AB</creatorcontrib><title>CHROMATOGRAPHY MATRIX</title><description>The present invention relates to a chromatography ligand defined by the following formula R1-R2-N(R3)-R4-R5 wherein R1 is a substituted or non-substituted phenyl group; R2 is a hydrocarbon chain comprising 0-4 carbon atoms; R3 is a hydrocarbon chain comprising 1-3 carbon atoms; R4 is a hydrocarbon chain comprising 1-5 carbon atoms; and R5 is OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.</description><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>SEPARATION</subject><subject>THEIR RELEVANT APPARATUS</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBB19gjy93UM8XcPcgzwiFQAMoM8I3gYWNMSc4pTeaE0N4OCm2uIs4duakF-fGpxQWJyal5qSbxrgKGFkbmZpaGToTERSgB08B7H</recordid><startdate>20161207</startdate><enddate>20161207</enddate><creator>MALOISEL, Jean-Luc, Amersham Biosciences AB</creator><creator>ENGSTRAND, Carina, Amersham Biosciences AB</creator><creator>FORSS, Annika, Amersham Biosciences AB</creator><creator>GLAD, Gunnar, Amersham Biosciences AB</creator><creator>JOHANSSON, Bo-Lennart, Amersham Biosciences AB</creator><creator>JOHANSSON, Hans J., Amersham Biosciences AB</creator><scope>EVB</scope></search><sort><creationdate>20161207</creationdate><title>CHROMATOGRAPHY MATRIX</title><author>MALOISEL, Jean-Luc, Amersham Biosciences AB ; ENGSTRAND, Carina, Amersham Biosciences AB ; FORSS, Annika, Amersham Biosciences AB ; GLAD, Gunnar, Amersham Biosciences AB ; JOHANSSON, Bo-Lennart, Amersham Biosciences AB ; JOHANSSON, Hans J., Amersham Biosciences AB</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP1827691B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2016</creationdate><topic>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>SEPARATION</topic><topic>THEIR RELEVANT APPARATUS</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>MALOISEL, Jean-Luc, Amersham Biosciences AB</creatorcontrib><creatorcontrib>ENGSTRAND, Carina, Amersham Biosciences AB</creatorcontrib><creatorcontrib>FORSS, Annika, Amersham Biosciences AB</creatorcontrib><creatorcontrib>GLAD, Gunnar, Amersham Biosciences AB</creatorcontrib><creatorcontrib>JOHANSSON, Bo-Lennart, Amersham Biosciences AB</creatorcontrib><creatorcontrib>JOHANSSON, Hans J., Amersham Biosciences AB</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MALOISEL, Jean-Luc, Amersham Biosciences AB</au><au>ENGSTRAND, Carina, Amersham Biosciences AB</au><au>FORSS, Annika, Amersham Biosciences AB</au><au>GLAD, Gunnar, Amersham Biosciences AB</au><au>JOHANSSON, Bo-Lennart, Amersham Biosciences AB</au><au>JOHANSSON, Hans J., Amersham Biosciences AB</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CHROMATOGRAPHY MATRIX</title><date>2016-12-07</date><risdate>2016</risdate><abstract>The present invention relates to a chromatography ligand defined by the following formula R1-R2-N(R3)-R4-R5 wherein R1 is a substituted or non-substituted phenyl group; R2 is a hydrocarbon chain comprising 0-4 carbon atoms; R3 is a hydrocarbon chain comprising 1-3 carbon atoms; R4 is a hydrocarbon chain comprising 1-5 carbon atoms; and R5 is OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL SEPARATION THEIR RELEVANT APPARATUS TRANSPORTING |
| title | CHROMATOGRAPHY MATRIX |
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