PEPTIDES AND APL-TYPE DERIVATIVES OF HSP60 AND PHARMACEUTICAL COMPOSITIONS

PEPTIDES AND APL-TYPE DERIVATIVES OF HSP60 AND PHARMACEUTICAL COMPOSITIONS

Peptides of human heat shock protein of 60 kDa, that constitute epitopes for T cells, as well as their derived peptides, which are modified at the contact sites with the MHC molecule, are useful to induce mechanisms of peripheral tolerance, in particular mechanisms of anergy or mediated by clones of...

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Hauptverfasser: LORENZO PEREZ, NORAILYS, MORERA CORDOVA, VIVIAN, PADRON PALOMARES, GABRIEL R, DOMINGUEZ HORTA, MARIA DEL CARMEN, LOPEZ MARIN, NELIA, COSME DIAZ, CARELIA, VAZQUEZ BONACHEA, ARIEL, MERINO GARCIA, NELSON J, HERNANDEZ GARCIA, ARIADNA, BARBERA BETANCOURT, ARIANA, SUAREZ ALBA, JOSE
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator LORENZO PEREZ, NORAILYS
MORERA CORDOVA, VIVIAN
PADRON PALOMARES, GABRIEL R
DOMINGUEZ HORTA, MARIA DEL CARMEN
LOPEZ MARIN, NELIA
COSME DIAZ, CARELIA
VAZQUEZ BONACHEA, ARIEL
MERINO GARCIA, NELSON J
HERNANDEZ GARCIA, ARIADNA
BARBERA BETANCOURT, ARIANA
SUAREZ ALBA, JOSE
description Peptides of human heat shock protein of 60 kDa, that constitute epitopes for T cells, as well as their derived peptides, which are modified at the contact sites with the MHC molecule, are useful to induce mechanisms of peripheral tolerance, in particular mechanisms of anergy or mediated by clones of regulatory T cells in patients with Rheumatoid Arthritis. The invention also refers pharmaceutical compositions comprising such peptides for the treatment of Rheumatoid Arthritis.
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language eng ; fre ; ger
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PEPTIDES AND APL-TYPE DERIVATIVES OF HSP60 AND PHARMACEUTICAL COMPOSITIONS
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