FAST RELEASE COMPOSITION INCLUDING MELT GRANULES OF A MOISTURE SENSITIVE DRUG AND PROCESS FOR MANUFACTURING THEREOF

FAST RELEASE COMPOSITION INCLUDING MELT GRANULES OF A MOISTURE SENSITIVE DRUG AND PROCESS FOR MANUFACTURING THEREOF

DPP-IV inhibitor compound for use in treating non-insulin-dependent diabetes mellitus, wherein the compound is (S)-1-[(3-hydroxy-1-admantyl)amino]acetyl-2-cyano-pyrrolidine of formula (IIC) and optionally pharmaceutical salts thereof, wherein the dosage of the compound of formula (IIC) is between 50...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SERAJUDDIN, Abu, T., M, JOSHI, Yatindra, KOWALSKI, James, KALB, Oskar
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:DPP-IV inhibitor compound for use in treating non-insulin-dependent diabetes mellitus, wherein the compound is (S)-1-[(3-hydroxy-1-admantyl)amino]acetyl-2-cyano-pyrrolidine of formula (IIC) and optionally pharmaceutical salts thereof, wherein the dosage of the compound of formula (IIC) is between 50 and 100 mg per day and the application of the compound of formula (IIC) occurs twice a day.