2,4-DI(AMINOPHENYL)PYRIMIDINE DERIVATIVES AS PLK INHIBITORS

The present invention encompasses compounds of general formula (1), wherein A, W, X, Y, Z, Ra, Rb, Rc, R1 and R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical c...

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Hauptverfasser: ZAHN, STEPHAN KARL, QUANT, JENS, JUERGEN, HAUPTMANN, RUDOLF, HERFURTH, LARS, ENGELHARDT, HARALD, BAUM, ANKE, GUERTLER, ULRICH, REISER, ULRICH, STEEGMAIER, MARTIN, SCHOOP, ANDREAS, SOLCA, FLAVIO, STADTMUELLER, HEINZ
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention encompasses compounds of general formula (1), wherein A, W, X, Y, Z, Ra, Rb, Rc, R1 and R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.