PGDS AS MODIFIERS OF THE PTEN PATHWAY AND METHODS OF USE

Human PGD genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of PGD are provided.

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Bibliographische Detailangaben
Hauptverfasser: SONG, CHUNYAN, OLLMANN, MICHAEL, MARTIN, BJERKE, LYNN, MARGARET
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Human PGD genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of PGD are provided.