ANTI-IL-13 ANTIBODIES, CRYSTALS OF ANTI-IL-13 ANTIBODIES AND OF COMPLEXES COMPRISING THEM
This application relates to antibodies, e.g ., humanized antibodies, and antigen-binding fragments thereof, that bind to interleukin-13 (IL-13), in particular, human IL-13, and their uses in regulating immune responses mediated by IL-13. The antibodies disclosed herein are useful in diagnosing, prev...
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creator | LIN, LAURA, LONG WILHELM, JAMES, M SHANE, TANIA PARRIS, KEVIN, D HU, ZHIXIANG DUMAS, JOHN STAHL, MARK TAN, XIANG-YANG TAM, AMY, SZE, PUI MOSYAK, LIDIA |
description | This application relates to antibodies, e.g ., humanized antibodies, and antigen-binding fragments thereof, that bind to interleukin-13 (IL-13), in particular, human IL-13, and their uses in regulating immune responses mediated by IL-13. The antibodies disclosed herein are useful in diagnosing, preventing, and/or treating a subject, e.g., a human patient, one or more IL-13-associated disorders, e.g., respiratory disorders ( e.g., asthma); atopic disorders ( e.g ., allergic rhinitis); inflammatory and/or autoimmune conditions of the skin ( e.g., atopic dermatitis), and gastrointestinal organs ( e.g., inflammatory bowel diseases (IBD)), as well as fibrotic and cancerous disorders. |
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subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | ANTI-IL-13 ANTIBODIES, CRYSTALS OF ANTI-IL-13 ANTIBODIES AND OF COMPLEXES COMPRISING THEM |
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