BENZOUREAS HAVING ANTI-DIABETIC ACTIVITY
Benzourea compounds of Formula I having aryl-(CH2)x-oxazolidinedione or aryl-(CH2)x-thiazolidinedione substituents on one of the N atoms of the benzourea ring, wherein x is 0 or 1, are PPAR gamma agonists or partial agonists and are useful in the treatment and control of type II diabetes, including...
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creator | LIU, WEIGUO WOOD, HAROLD, B LAU-PHUA, FIONA WAI-YU |
description | Benzourea compounds of Formula I having aryl-(CH2)x-oxazolidinedione or aryl-(CH2)x-thiazolidinedione substituents on one of the N atoms of the benzourea ring, wherein x is 0 or 1, are PPAR gamma agonists or partial agonists and are useful in the treatment and control of type II diabetes, including hyperglycemia and other symptoms such as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity, that are often associated with type 2 diabetes. I |
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I</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2007</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNBwcvWL8g8NcnUMVvBwDPP0c1dw9Avx1HXxdHRyDfF0VnB0DvEM8wyJ5GFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BhuamxiZGxo5GxkQoAQDK8iPB</recordid><startdate>20070221</startdate><enddate>20070221</enddate><creator>LIU, WEIGUO</creator><creator>WOOD, HAROLD, B</creator><creator>LAU-PHUA, FIONA WAI-YU</creator><scope>EVB</scope></search><sort><creationdate>20070221</creationdate><title>BENZOUREAS HAVING ANTI-DIABETIC ACTIVITY</title><author>LIU, WEIGUO ; WOOD, HAROLD, B ; LAU-PHUA, FIONA WAI-YU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP1753423A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2007</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LIU, WEIGUO</creatorcontrib><creatorcontrib>WOOD, HAROLD, B</creatorcontrib><creatorcontrib>LAU-PHUA, FIONA WAI-YU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LIU, WEIGUO</au><au>WOOD, HAROLD, B</au><au>LAU-PHUA, FIONA WAI-YU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BENZOUREAS HAVING ANTI-DIABETIC ACTIVITY</title><date>2007-02-21</date><risdate>2007</risdate><abstract>Benzourea compounds of Formula I having aryl-(CH2)x-oxazolidinedione or aryl-(CH2)x-thiazolidinedione substituents on one of the N atoms of the benzourea ring, wherein x is 0 or 1, are PPAR gamma agonists or partial agonists and are useful in the treatment and control of type II diabetes, including hyperglycemia and other symptoms such as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity, that are often associated with type 2 diabetes. 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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | BENZOUREAS HAVING ANTI-DIABETIC ACTIVITY |
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