METHOD OF MAKING SILICONE PRESSURE SENSITIVE ADHESIVES FOR DELIVERING HYDROPHILIC DRUGS USING A SILICONE POLYETHER

A hydrophobic matrix is prepared by forming a semi-solid composition containing a solid powdered hydrophilic drug and/or a solid powdered hydrophilic excipient, and a silicone polyether, and then adding the semi-solid composition to a silicone pressure sensitive adhesive or a solution containing a s...

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Hauptverfasser: RAUL, VICTOR, ALBERT, THOMAS, XAVIER, SCHALAU, GERALD, K. II
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creator RAUL, VICTOR, ALBERT
THOMAS, XAVIER
SCHALAU, GERALD, K. II
description A hydrophobic matrix is prepared by forming a semi-solid composition containing a solid powdered hydrophilic drug and/or a solid powdered hydrophilic excipient, and a silicone polyether, and then adding the semi-solid composition to a silicone pressure sensitive adhesive or a solution containing a solvent and a silicone pressure sensitive adhesive, and mixing the composition and the silicone pressure sensitive adhesive or the solution containing the solvent and the silicone pressure sensitive adhesive together to form the hydrophobic matrix. The hydrophobic matrix can be applied to a substrate, typically the human skin by means of a transdermal patch for continuous and controlled transdermal administration of drugs.
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language eng ; fre ; ger
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subjects CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
title METHOD OF MAKING SILICONE PRESSURE SENSITIVE ADHESIVES FOR DELIVERING HYDROPHILIC DRUGS USING A SILICONE POLYETHER
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