Method for the production of non-immunogenic proteins
The invention relates to a specific method of rendering therapeutic non-human proteins non or les immunogenic compared to a given human individual by identifying and modifying peptides within T-cell epitopes of said proteins, which bind to MHC class II molecules or show the ability to stimulate T-ce...
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| creator | CARTER, GRAHAM CARR, FRANCIS JOSEPH ADAIR, FIONA HAMILTON, ANITA A |
| description | The invention relates to a specific method of rendering therapeutic non-human proteins non or les immunogenic compared to a given human individual by identifying and modifying peptides within T-cell epitopes of said proteins, which bind to MHC class II molecules or show the ability to stimulate T-cells via presentation on MHC class II. |
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fre ; ger</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; TESTING</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130515&DB=EPODOC&CC=EP&NR=1724282B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130515&DB=EPODOC&CC=EP&NR=1724282B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CARTER, GRAHAM</creatorcontrib><creatorcontrib>CARR, FRANCIS JOSEPH</creatorcontrib><creatorcontrib>ADAIR, FIONA</creatorcontrib><creatorcontrib>HAMILTON, ANITA A</creatorcontrib><title>Method for the production of non-immunogenic proteins</title><description>The invention relates to a specific method of rendering therapeutic non-human proteins non or les immunogenic compared to a given human individual by identifying and modifying peptides within T-cell epitopes of said proteins, which bind to MHC class II molecules or show the ability to stimulate T-cells via presentation on MHC class II.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDD1TS3JyE9RSMsvUijJSFUoKMpPKU0uyczPU8hPU8jLz9PNzM0tzctPT83LTAbJlqRm5hXzMLCmJeYUp_JCaW4GBTfXEGcP3dSC_PjU4oLE5NS81JJ41wBDcyMTIwsjJ0NjIpQAACKDLQY</recordid><startdate>20130515</startdate><enddate>20130515</enddate><creator>CARTER, GRAHAM</creator><creator>CARR, FRANCIS JOSEPH</creator><creator>ADAIR, FIONA</creator><creator>HAMILTON, ANITA A</creator><scope>EVB</scope></search><sort><creationdate>20130515</creationdate><title>Method for the production of non-immunogenic proteins</title><author>CARTER, GRAHAM ; 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| language | eng ; fre ; ger |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING |
| title | Method for the production of non-immunogenic proteins |
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