SELECTIVE KINASE INHIBITORS
A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof, wherein A represents a variety of six membered nitrogen containing heterocyclic rings, Q is a bond, halogen, C1-4 alkyl, O, S, SO2, CO or CS and X1, X2, X...
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| creator | KLING, MARCEL, ROBERT BU, XIANYONG WILKS, ANDREW, FREDERICK STYLES, MICHELLE LEANNE BURNS, CHRISTOPHER, JOHN TREUTLEIN, HERBERT, RUDOLF ZENG, JUN |
| description | A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof, wherein A represents a variety of six membered nitrogen containing heterocyclic rings, Q is a bond, halogen, C1-4 alkyl, O, S, SO2, CO or CS and X1, X2, X3 and X4 are optionally substituted by 9 specific substituents or one can be nitrogen. Compositions comprising a carrier and at least one compound of formula (I) are also provided. Further provided are methods of treating tyrosine kinase-associated disease states by administering a compound of formula (I) and methods of suppressing the immune system of a subject by administering a compound of formula (I). |
| format | Patent |
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Compositions comprising a carrier and at least one compound of formula (I) are also provided. Further provided are methods of treating tyrosine kinase-associated disease states by administering a compound of formula (I) and methods of suppressing the immune system of a subject by administering a compound of formula (I).</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090805&DB=EPODOC&CC=EP&NR=1704145A4$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090805&DB=EPODOC&CC=EP&NR=1704145A4$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KLING, MARCEL, ROBERT</creatorcontrib><creatorcontrib>BU, XIANYONG</creatorcontrib><creatorcontrib>WILKS, ANDREW, FREDERICK</creatorcontrib><creatorcontrib>STYLES, MICHELLE LEANNE</creatorcontrib><creatorcontrib>BURNS, CHRISTOPHER, JOHN</creatorcontrib><creatorcontrib>TREUTLEIN, HERBERT, RUDOLF</creatorcontrib><creatorcontrib>ZENG, JUN</creatorcontrib><title>SELECTIVE KINASE INHIBITORS</title><description>A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof, wherein A represents a variety of six membered nitrogen containing heterocyclic rings, Q is a bond, halogen, C1-4 alkyl, O, S, SO2, CO or CS and X1, X2, X3 and X4 are optionally substituted by 9 specific substituents or one can be nitrogen. Compositions comprising a carrier and at least one compound of formula (I) are also provided. Further provided are methods of treating tyrosine kinase-associated disease states by administering a compound of formula (I) and methods of suppressing the immune system of a subject by administering a compound of formula (I).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJAOdvVxdQ7xDHNV8Pb0cwx2VfD08_B08gzxDwrmYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgGG5gYmhiamjibGRCgBABzcIDY</recordid><startdate>20090805</startdate><enddate>20090805</enddate><creator>KLING, MARCEL, ROBERT</creator><creator>BU, XIANYONG</creator><creator>WILKS, ANDREW, FREDERICK</creator><creator>STYLES, MICHELLE LEANNE</creator><creator>BURNS, CHRISTOPHER, JOHN</creator><creator>TREUTLEIN, HERBERT, RUDOLF</creator><creator>ZENG, JUN</creator><scope>EVB</scope></search><sort><creationdate>20090805</creationdate><title>SELECTIVE KINASE INHIBITORS</title><author>KLING, MARCEL, ROBERT ; BU, XIANYONG ; WILKS, ANDREW, FREDERICK ; STYLES, MICHELLE LEANNE ; BURNS, CHRISTOPHER, JOHN ; TREUTLEIN, HERBERT, RUDOLF ; ZENG, JUN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP1704145A43</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2009</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KLING, MARCEL, ROBERT</creatorcontrib><creatorcontrib>BU, XIANYONG</creatorcontrib><creatorcontrib>WILKS, ANDREW, FREDERICK</creatorcontrib><creatorcontrib>STYLES, MICHELLE LEANNE</creatorcontrib><creatorcontrib>BURNS, CHRISTOPHER, JOHN</creatorcontrib><creatorcontrib>TREUTLEIN, HERBERT, RUDOLF</creatorcontrib><creatorcontrib>ZENG, JUN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KLING, MARCEL, ROBERT</au><au>BU, XIANYONG</au><au>WILKS, ANDREW, FREDERICK</au><au>STYLES, MICHELLE LEANNE</au><au>BURNS, CHRISTOPHER, JOHN</au><au>TREUTLEIN, HERBERT, RUDOLF</au><au>ZENG, JUN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SELECTIVE KINASE INHIBITORS</title><date>2009-08-05</date><risdate>2009</risdate><abstract>A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof, wherein A represents a variety of six membered nitrogen containing heterocyclic rings, Q is a bond, halogen, C1-4 alkyl, O, S, SO2, CO or CS and X1, X2, X3 and X4 are optionally substituted by 9 specific substituents or one can be nitrogen. Compositions comprising a carrier and at least one compound of formula (I) are also provided. Further provided are methods of treating tyrosine kinase-associated disease states by administering a compound of formula (I) and methods of suppressing the immune system of a subject by administering a compound of formula (I).</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SELECTIVE KINASE INHIBITORS |
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