MACROCYCLIC CARBOXYLIC ACIDS AND ACYLSULFONAMIDES AS INHIBITORS OF HCV REPLICATION

The present application provides compounds of the general formulas I-IX as defined herein, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present application further provides treatment methods, including methods of treating a hepatitis C virus infe...

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Hauptverfasser: ANDREWS, STEVEN WADE, KENNEDY, APRIL LAYNE, WENGLOWSKY, STEVEN MARK, WOODARD, BENJAMIN T, JIANG, YUTONG, CONDROSKI, KEVIN RONALD, MADDURU, MACHENDER R, JOSEY, JOHN ANTHONY, DOHERTY, GEORGE ANDREW, BLATT, LAWRENCE M, STENGEL, PETER JOHN
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creator ANDREWS, STEVEN WADE
KENNEDY, APRIL LAYNE
WENGLOWSKY, STEVEN MARK
WOODARD, BENJAMIN T
JIANG, YUTONG
CONDROSKI, KEVIN RONALD
MADDURU, MACHENDER R
JOSEY, JOHN ANTHONY
DOHERTY, GEORGE ANDREW
BLATT, LAWRENCE M
STENGEL, PETER JOHN
description The present application provides compounds of the general formulas I-IX as defined herein, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present application further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
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language eng ; fre ; ger
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subjects CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
title MACROCYCLIC CARBOXYLIC ACIDS AND ACYLSULFONAMIDES AS INHIBITORS OF HCV REPLICATION
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