PPAR-ACTIVATING COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

A compound represented by the following formula (1): (wherein each of R 1 and R 2 , which may be identical to or different from each other, represents a hydrogen atom, a methyl group, or an ethyl group; each of R 3a , R 3b , R 4a , and R 4b , which may be identical to or different from each other, r...

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Hauptverfasser: ARAKI, TAKAAKI, OKUDA, AYUMU, TOMA, TSUTOMU, ABE, KAZUTOYO, NISHIKAWA, MASAHIRO, OZAWA, HIDEFUMI, YAMAZAKI, YUKIYOSHI, ODA, SOICHI
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Sprache:eng ; fre ; ger
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creator ARAKI, TAKAAKI
OKUDA, AYUMU
TOMA, TSUTOMU
ABE, KAZUTOYO
NISHIKAWA, MASAHIRO
OZAWA, HIDEFUMI
YAMAZAKI, YUKIYOSHI
ODA, SOICHI
description A compound represented by the following formula (1): (wherein each of R 1 and R 2 , which may be identical to or different from each other, represents a hydrogen atom, a methyl group, or an ethyl group; each of R 3a , R 3b , R 4a , and R 4b , which may be identical to or different from each other, represents a hydrogen atom, a halogen atom, a nitro group, a hydroxyl group, a C 1-4 alkyl group, a trifluoromethyl group, a C 1-4 alkoxy group, a C 1-4 alkylcarbonyloxy group, a di-C 1-4 alkylamino group, a C 1-4 alkylsulfonyloxy group, a C 1-4 alkylsulfonyl group, a C 1-4 alkylsulfinyl group, or a C 1-4 alkylthio group, or R 3a and R 3b , or R 4a and R 4b may be linked together to form an alkylenedioxy group; X represents an oxygen atom, a sulfur atom, or N-R 5 (R 5 represents a hydrogen atom, a C 1-4 alkyl group, a C 1-4 alkylsulfonyl group, or a C 1-4 alkyloxycarbonyl group); Y represents an oxygen atom, S(O) 1 (1 is a number of 0 to 2), a carbonyl group, a carbonylamino group, an aminocarbonyl group, a sulfonylamino group, or an aminosulfonyl group; Z represents CH or N; n is a number of 1 to 6; and m is a number of 2 to 6) or a salt thereof; and therapeutic drugs containing any of such a compound or salt.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PPAR-ACTIVATING COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
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