COX-2 AND FAAH INHIBITORS

The invention features compounds that inhibit COX-2 and/or FAAH. The COX-2 inhibitors are selective COX-2 inhibitors in that they are selective for COX-2 compared to COX-1. Certain of the FAAH inhibitors are selective for FAAH relative to COX-2. Certain of the COX-2 inhibitors, in addition for being...

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Hauptverfasser: CHEN, BARBARA, CURRIE, MARK, G, PEARSON, JAMES, PHILIP, MILNE, TODD, G, TALLEY, JOHN, JEFFREY, CALI, BRIAN, M, BARTOLINI, WILMIN, CHIEN, YUEH-TYNG, ZIMMERMAN, CRAIG
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creator CHEN, BARBARA
CURRIE, MARK, G
PEARSON, JAMES, PHILIP
MILNE, TODD, G
TALLEY, JOHN, JEFFREY
CALI, BRIAN, M
BARTOLINI, WILMIN
CHIEN, YUEH-TYNG
ZIMMERMAN, CRAIG
description The invention features compounds that inhibit COX-2 and/or FAAH. The COX-2 inhibitors are selective COX-2 inhibitors in that they are selective for COX-2 compared to COX-1. Certain of the FAAH inhibitors are selective for FAAH relative to COX-2. Certain of the COX-2 inhibitors, in addition for being selective for COX-2 relative to COX-1, are selective for COX-2 relative to FAAH.
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subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COX-2 AND FAAH INHIBITORS
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