FEEDBACK-RESISTANT MEVALONATE KINASES

The present invention relates to modified mevalonate kinases that are less sensitive to feedback inhibition, and to polynucleotides encoding them. The invention further pertains to vectors comprising these polynucleotides and host cells containing such vectors. The invention provides a method for pr...

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Hauptverfasser: LEHMANN, MARTIN, HUEMBELIN, MARKUS, LOPEZ-ULIBARRI, RUAL, WYSS, MARKUS, BAI, RENYUNAN
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creator LEHMANN, MARTIN
HUEMBELIN, MARKUS
LOPEZ-ULIBARRI, RUAL
WYSS, MARKUS
BAI, RENYUNAN
description The present invention relates to modified mevalonate kinases that are less sensitive to feedback inhibition, and to polynucleotides encoding them. The invention further pertains to vectors comprising these polynucleotides and host cells containing such vectors. The invention provides a method for producing the modified enzyme and a method for producing isoprenoid compounds.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title FEEDBACK-RESISTANT MEVALONATE KINASES
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