CRYSTAL STRUCTURE OF ANGIOTENSIN-CONVERTING ENZYME-RELATED CARBOXYPEPTIDASE

The invention relates to molecules or molecular complexes which comprise binding pockets of angiotensin-converting enzyme-related carboxypeptidase or its homologues. The invention relates to a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. T...

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Hauptverfasser: WILLIAMS, DAVID, H, RYAN, M., DOMINIC, STAKER, BART, LEE, MENON, SAURABH, PRABHAKAR, FISHER, MARTIN, PANTOLIANO, MICHAEL, W, PRASAD, G., SRIDHAR, TANG, JIN, TOWLER, PAUL, S
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creator WILLIAMS, DAVID, H
RYAN, M., DOMINIC
STAKER, BART, LEE
MENON, SAURABH, PRABHAKAR
FISHER, MARTIN
PANTOLIANO, MICHAEL, W
PRASAD, G., SRIDHAR
TANG, JIN
TOWLER, PAUL, S
description The invention relates to molecules or molecular complexes which comprise binding pockets of angiotensin-converting enzyme-related carboxypeptidase or its homologues. The invention relates to a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. The invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. The invention relates to methods of using the structure coordinates to screen for and design compounds that bind to angiotensin-converting enzyme-related carboxypeptidase protein or homologues thereof. The invention also relates to crystallizable compositions and crystals comprising angiotensin-converting enzyme-related carboxypeptidase protein or angiotensin-converting enzyme-related carboxypeptidase protein complexes.
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language eng ; fre ; ger
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title CRYSTAL STRUCTURE OF ANGIOTENSIN-CONVERTING ENZYME-RELATED CARBOXYPEPTIDASE
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