MICROFLUIDIZED OIL-IN-WATER EMULSIONS AND VACCINE COMPOSITIONS

This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsically. Methods of preparing the emu...

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Hauptverfasser: KREBS, RICHARD LEE, MANNAN, RAMASAMY M, DOMINOWSKI, PAUL J, KLOSE, PAMELA KAY
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creator KREBS, RICHARD LEE
MANNAN, RAMASAMY M
DOMINOWSKI, PAUL J
KLOSE, PAMELA KAY
description This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsically. Methods of preparing the emulsions and vaccines are also provided by the present invention.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title MICROFLUIDIZED OIL-IN-WATER EMULSIONS AND VACCINE COMPOSITIONS
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