PROCESS AND INTERMEDIATES TO PREPARE 17.BETA.-HYDROXY-7.ALFA.-METHYL-19-NOR-17.ALFA.-PREGN-5(10)-EN-20-YN-3-ONE

The present invention is a process for the preparation of 17beta-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one (17alpha-ethynyl-17beta-hydroxy-7alpha-methyl-5(10)-estren-3-one, tibolone) of formula 1, which comprises hydrolysis of 17alpha-ethynyl-17beta-hydroxy-7alpha-methyl-5(10)-...

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Bibliographische Detailangaben

Hauptverfasser:	KUTNER, ANDRZEJ, FITAK, HANNA, MARTYNOW, JACEK, WOJCIECHOWSKA, WANDA, SZELEJEWSKI, WIESLAW
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY STEROIDS
Online-Zugang:	Volltext bestellen
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